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KMID : 0356619930080030351
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Journal of Korean Society of Endocrinology
1993 Volume.8 No. 3 p.351 ~ p.355
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A Case of Osteoporosis Associated with Pernicious Anemia
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김상욱
최승원/이정신/박중열/이기업/김기수
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Abstract
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ABSTRACT
@EN A few studies strongly suggest that pernicious anemia is a risk factor for osteoporosis, but the mechanism is unknown.
Recently we experienced a 65-year-old female with pernicious anemia and osteoporosis. She had multiple compression fractures of thoracolumbar vertebrae and low bone mineral density of spine and femur by dual photon absorptiometry.
Pernicious anemia was confirmed with low serum vitamin B12 level and characteristic bone marrow findings. She did not have other secondary causes of osteoporosis other than pernicious anemia. Although we do not believe pernicous anemia is solely
responsible for osteoporosis of this patient, it must have contributed some to the development of the disease.
In summary, pernicious anemia is a risk factor for osteoporosis and optimal evaluation and management of bone loss should be done in patients with pernicious anemia, especially in postmenopausal state (J Kor Soc Endocrinol 8:351~355, 1993).
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